Rob, I've collected something or other -- coins/stamps, wines, decorative eggs, books, bourbons/whiskeys -- almost all of my life. So, I understand.
The coins/stamps went when I had obtained everything I could afford to buy, and my options were to lock 'em up in bank vault where nobody could enjoy them or let someone else enjoy them (AND turn them into some cash for other purposes ).
The wines have (mostly) disappeared gradually over the years, of course, with meals I've prepared, Gazebos/gatherings I've shared, or as gifts.
The eggs went via eBay when they were taking up too much space.
The books do get reread occasionally and can be organized, in a sense, in bookcases, etc., but even some of those get traded or given away.
As for the whiskeys -- well, I've opened some Wild Turkey 12yo and the Pappy 23s (and a few others) to share with some of the fine folks here, and while I regret their passing, I would regret even more not having enjoyed the whiskey or the company.
My most prized bottle at present, Rob, is a W.L. Weller 8yo BIB distilled in 1940. I don't sit around wondering what it's worth as part of my estate. I sit around wondering when will be the appropriate time to open it.
Don't cheat yourself. The only question about opening and drinking 'em is 'when'.